ACTH is actually a cleavage product of pro-opiomelanocortin (POMC), which is made by corticotropes and processed primarily into ACTH in these cells. Remember that the acidophils include two different cell types, somatotropes (growth hormone) and mammotropes (prolactin), while the basophils include gonadotropes (FSH and LH), thyrotropes (TSH) and corticotropes (ACTH). Theacidophils stain red or orange-red, while the basophils stain various shades of blue or blue-gray. The cells are arranged in irregular clusters or cords and are distinguishable by their staining as either acidophils, basophils, or chromophobes. Study the pars distalis (anterior lobe) in the slide stained with Masson trichrome slide 226 pars distalis View Image. Slide 227 Pituitary gland Masson sagittal View Virtual Slide Slide 226 Pituitary gland H&E sagittal View Virtual Slide Slide 226 Pituitary gland H&E cross View Virtual Slide Slide 226 Pituitary gland Masson cross View Virtual Slide Pars distalis (aka anterior pituitary or adenohypophysis) The two classes of anterior pituitary cells (acidophils and basophils) are most easily distinguished with Masson trichrome staining, but you should also see how they look with routine H&E staining. These slides show mostly pars distalis, but also have a small area of neurohypophysis (either pars nervosa or infundibular stalk) on one side (see slide orientation diagrams) and are stained in alternate sets with H&E or with Masson trichrome.
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